Dr. Mandavi Rai Successful IVF Treatment In Noida, Delhi NCR

How does IVF work?

IVF stands for in vitro fertilization. It’s one of the more widely known types of assisted reproductive technology (ART). IVF works by using a combination of medicines and surgical procedures to help sperm fertilize an egg, and help the fertilized egg implant in your uterus.

IVF has many steps, and it takes several months to complete the whole process. It sometimes works on the first try, but many people need more than 1 round of IVF to get pregnant. IVF definitely increases your chances of pregnancy if you’re having fertility problems, but there’s no guarantee — everyone’s body is different and IVF won’t work for everyone.

Why is IVF performed?

People choose IVF for many reasons, including infertility issues or when one partner has an existing health condition. Some people will try IVF after other fertility methods have failed or if they’re at an advanced maternal age. IVF is also a reproductive option for same-sex couples or people who wish to have a baby without a partner.

IVF is an option if you or your partner has:

Blocked or damaged fallopian tubes.
Endometriosis
Low sperm count or other sperm impairments.
PCOS or POF
Fibroids
Problems with your uterus.
Risk of passing on a genetic disease or disorder.
Unexplained Infertility
Are using an egg donor or a gestational surrogate

What are the steps of IVF treatment?

IVF can be broken down into the following steps:

Ovarian stimulation

During each natural cycle in a healthy person of reproductive age, a group of eggs begins to mature each month. Typically, only one egg becomes mature enough to ovulate. The remaining immature eggs in that group disintegrate.

During your IVF cycle, you’ll take injectable hormone medications to encourage the entire group of that cycle’s eggs to mature simultaneously and fully. This means, instead of having just one egg (like in a natural cycle), you may have many eggs. The type, dosage and frequency of medications prescribed will be tailored to you as an individual based on your medical history, age, AMH (anti-mullerian hormone) level and your response to ovarian stimulation during previous IVF cycles.

The other steps in the ovarian stimulation process include:

Monitoring: Your ovaries’ response to the medications is monitored by ultrasound and blood hormone levels. Monitoring can occur daily or every few days over two weeks. Most stimulations last between eight and 14 days. At monitoring appointments, healthcare providers use ultrasound to look at your uterus and ovaries. The eggs themselves are too small to be visible with ultrasound. But, your healthcare providers will measure the size and number of growing ovarian follicles. Follicles are little sacks within your ovaries that should each contain a single egg. The size of each follicle indicates the maturity of the egg it contains. Most follicles greater than 14 millimeters (mm) contain a mature egg. The eggs contained within follicles less than 14 mm are more likely be immature and won’t fertilize.
Trigger shot: When your eggs are ready for final maturation (determined by your ultrasound and hormone levels), a “trigger shot” is given to finalize the maturation of your eggs in preparation for egg retrieval. You’ll be instructed to administer the trigger shot exactly 36 hours before your scheduled egg retrieval time.

Egg retrieval

Your healthcare provider uses an ultrasound to guide a thin needle into each of your ovaries through your vagina. The needle is connected to a suction device used to pull your eggs out of each follicle.
Your eggs are placed in a dish containing a special solution. The dish is then put in an incubator (controlled environment).
Medication and mild sedation are used to reduce discomfort during this procedure.
Egg retrieval is done 36 hours after your last hormone injection, the “trigger shot.”

Fertilization

The afternoon after your egg retrieval procedure, the embryologist will try to fertilize all mature eggs using intracytoplasmic sperm injection, or ICSI. This means that sperm will be injected into each mature egg. Immature eggs cannot have ICSI performed on them. The immature eggs will be placed in a dish with sperm and nutrients. Immature eggs rarely finish their maturation process in the dish. If an immature egg does mature, the sperm in the dish can then attempt to fertilize the egg.

On average, 70% of mature eggs will fertilize. For example, if 10 mature eggs are retrieved, about seven will fertilize. If successful, the fertilized egg will become an embryo.

If there are an exceedingly large number of eggs or you don’t want all eggs fertilized, some eggs may be frozen before fertilization for future use.

Embryo development

Over the next five to six days, the development of your embryos will be carefully monitored.

Your embryo must overcome significant hurdles to become an embryo suitable for transfer to your uterus. On average, 50% of fertilized embryos progress to the blastocyst stage. This is the stage most suitable for transfer to your uterus. For example, if seven eggs were fertilized, three or four of them might develop to the blastocyst stage. The remaining 50% typically fail to progress and are discarded.

All embryos suitable for transfer will be frozen on day five or six of fertilization to be used for future embryo transfers.

Embryo transfer

There are two kinds of embryo transfers: fresh embryo transfer and frozen embryo transfer. Your healthcare provider can discuss using fresh or frozen embryos with you and decide what’s best based on your unique situation. Both frozen and fresh embryo transfers follow the same transfer process. The main difference is implied by the name.

A fresh embryo transfer means your embryo is inserted into your uterus between three and seven days after the egg retrieval procedure. This embryo hasn’t been frozen and is “fresh.”

A frozen embryo transfer means that frozen embryos (from a previous IVF cycle or donor eggs) are thawed and inserted into your uterus. This is a more common practice for logistical reasons and because this method is more likely to result in a live birth. Frozen embryo transfers can occur years after egg retrieval and fertilization.

As part of the first step in a frozen embryo transfer, you’ll take oral, injectable, vaginal or transdermal hormones to prepare your uterus for accepting an embryo. Usually, this is 14 to 21 days of oral medication followed by six days of injections. Typically, you’ll have two or three appointments during this time to monitor the readiness of your uterus with ultrasound and to measure your hormone levels with a blood test. When your uterus is ready, you’ll be scheduled for the embryo transfer procedure.

The process is similar if you’re using fresh embryos, except embryo transfer happens within three to five days of being retrieved.

The embryo transfer is a simple procedure that doesn’t require anesthesia. It feels similar to a pelvic exam or Pap smear. A speculum is placed within the vagina, and a thin catheter is inserted through the cervix into the uterus. A syringe attached to the other end of the catheter contains one or more embryos. The embryos are injected it the uterus through the catheter. The procedure typically takes less than 10 minutes.

Pregnancy

Pregnancy occurs when the embryo implants itself into the lining of your uterus. Your healthcare provider will use a blood test to determine if you’re pregnant approximately nine to 14 days after embryo transfer.

What are the risks of IVF?

There are several risks associated with IVF treatment:

Multiple births: A pregnancy with multiple babies carries a higher risk of premature labor.
Premature Delivery: You may have a slightly higher risk of your baby being born early or at a lower birth weight.
Miscarriage: The rate of miscarriage is about the same as pregnancies from natural conception.
Ectopic pregnancy: This is a condition where your fertilized egg implants outside of your uterus.
Complications during egg retrieval: Bleeding, infection and damage to your bladder, bowel or reproductive organs during the egg retrieval process.
Ovarian hyperstimulation syndrome (OHSS): A rare condition that causes abdominal pain, nausea, vomiting, diarrhea, rapid weight gain, bloating, shortness of breath and inability to urinate.

What are the most common side effects of IVF?

Some experience side effects from the fertility medications used during the ovulation stimulation phase of IVF. These include:

Nausea and vomiting.
Hot flashes.
Headaches.
Enlargement of their ovaries.
Abdominal Pain
Bruising from IVF injections.

After the transfer of your embryo, you should be able to resume normal activities. Your ovaries will be enlarged, and some discomfort may occur. Common side effects after embryo transfer are:

Constipation
Bloating.
Cramping.
Breast tenderness (from high estrogen).
Spotting.

IVF can be difficult — both physically and emotionally. Many people doing IVF treatment struggle with depression and anxiety. Infertility struggles and IVF can leave people feeling disappointed or overwhelmed. Talk with your healthcare provider about how you’re feeling so they can offer support through the process.

What is the success rate of IVF by age?

Data collected in the U.S .is measured per egg retrieval, not per cycle. The average percentage of live births per egg retrieval in 2019 was:

Younger than 35: 46.7%
Ages 35 to 37: 34.2%
Ages 38 to 40: 21.6%
Ages 41 to 42: 10.6%
Ages 43 and up: 3.2%

Why do IVF treatments fail?

IVF treatments can fail for many reasons and at any step in the IVF process. Some reasons an IVF cycle fails are:

Premature ovulation.
No eggs are developing.
Too many eggs are developing.
Egg isn’t fertilized by sperm.
Sperm quality.
Embryo stops growing or will not implant.
Problems with egg retrieval or embryo transfer.

Your healthcare provider will be able to examine each step of the process with you and determine how to best move forward with future treatments.

Can IVF cause birth defects?

It’s not entirely known if IVF alone is responsible for birth defects. For non-IVF pregnancies, around 2% of all children will be born with a birth defect. Some studies show a slightly higher risk for babies born through IVF. This could be due to delayed conception or related to the underlying cause of infertility.

Embark on Your IVF Journey in Noida:

We invite you to take the first step toward fulfilling your dreams of parenthood by partnering with our renowned IVF center in Noida at INDIRA IVF NOIDA with Dr Mandavi Rai. Our compassionate team is here to provide unwavering support, innovative solutions, and expert care throughout your fertility journey. Contact us today to schedule a consultation and embark on a pathway to parenthood that is backed by excellence, compassion, and success. Your future family is waiting, and we’re here to help you make it a reality.

IVF

How does IVF work?

Why is IVF performed?

What are the steps of IVF treatment?

Ovarian stimulation

Egg retrieval

Fertilization

Embryo development

Embryo transfer

Pregnancy

What are the risks of IVF?

What are the most common side effects of IVF?

What is the success rate of IVF by age?

Why do IVF treatments fail?

Can IVF cause birth defects?

Embark on Your IVF Journey in Noida:

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