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PRP

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What is Platelet Rich Plasma (PRP)?

Platelet-rich plasma (PRP) is a cutting-edge medical technique gaining prominence in various fields, including fertility treatments such as In Vitro Fertilization (IVF). PRP involves isolating and concentrating platelets from a patient’s blood, which are then re-injected into specific areas to promote tissue regeneration, healing, and cell growth. This regenerative therapy has shown promise in enhancing fertility outcomes and addressing certain reproductive issues.

 

Who Needs PRP?

PRP can be beneficial for individuals facing fertility challenges due to various factors. Some scenarios where PRP may be considered include:

  1. Low ovarian reserve: Women with a limited number of viable eggs may opt for PRP to improve the health and quality of their existing follicles.
  2. Thin Endometrial Lining: PRP can stimulate the growth of the endometrial lining, addressing the issue of inadequate thickness, which is crucial for embryo implantation.
  3. Recurrent implantation faliure(RIF): Couples who have experienced multiple unsuccessful IVF cycles may explore PRP as an adjunctive therapy to improve embryo implantation rates.
  4. Male Factor Infertility: PRP can be applied in cases of , as it may enhance sperm quality and function.
  5. Unexplained infertility: When the cause of infertility remains unclear, PRP may be considered as a complementary treatment to improve overall reproductive health.

How is PRP Done in IVF?

The process of PRP administration in the context of IVF involves several steps:

  1. Blood Collection: A small amount of the patient’s blood is drawn, typically from the arm, using a standard blood collection technique.
  2. Centrifugation: The collected blood is then processed in a centrifuge, a specialized machine that spins at high speeds to separate its components. This step isolates the platelet-rich portion of the blood from other components like red blood cells and plasma.
  3. Platelet Activation: After isolation, the platelet-rich portion is activated using calcium chloride or a similar substance. Activation prompts the release of growth factors from the platelets, which are essential for tissue repair and regeneration.
  4. Injection: The activated PRP is then carefully injected into the target area. In IVF, this could include the ovaries to enhance follicle development or the uterus to improve the endometrial lining.
  5. Monitoring and IVF Procedures: Following PRP administration, patients typically undergo standard IVF procedures, including controlled ovarian stimulation, egg retrieval, fertilization, and embryo transfer.

Does PRP Increase Endometrial Thickness?

Yes, PRP has shown promise in increasing endometrial thickness, a critical factor in successful embryo implantation during IVF and natural conception. The growth factors released by platelets in PRP stimulate the regeneration of endometrial tissue, leading to a thicker and more receptive uterine lining.

Research and clinical studies have demonstrated that PRP injections into the uterine lining can lead to significant improvements in endometrial thickness. For individuals struggling with thin endometrial linings, this approach can be a valuable addition to their fertility treatment plan.

 

Risks of PRP in IVF

Like any medical procedure, PRP in IVF carries some inherent risks:

  1. Infection: There is a minimal risk of infection at the injection site. Strict sterile techniques should be followed to minimize this risk.
  2. Pain or Discomfort: Patients may experience mild pain, swelling, or discomfort at the injection site, which is generally temporary.
  3. Bruising: Some patients may develop bruises at the injection site, but these typically resolve on their own.
  4. Allergic Reactions: While rare, allergic reactions to PRP components can occur. Patients should inform their healthcare provider of any known allergies.
  5. No Guarantee of Success: It’s important to note that PRP is not a guaranteed solution for fertility issues. The treatment may not work for everyone, and outcomes can vary.
  6. Financial Considerations: The cost of PRP can be a potential risk if it does not lead to the desired fertility improvements.
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Benefits of PRP in IVF

PRP offers several potential benefits when incorporated into IVF treatments:

  1. Improved Egg Quality: PRP can enhance the quality of eggs, which is particularly beneficial for women with diminished ovarian reserve or older individuals.
  2. Enhanced Endometrial Lining: PRP can stimulate the growth of the endometrial lining, increasing the chances of successful embryo implantation.
  3. Natural Approach: PRP is derived from the patient’s blood, making it a natural and autologous therapy with minimal risk of allergic reactions or side effects.
  4. Customized Treatment: PRP can be tailored to address specific fertility issues, making it a personalized treatment option.
  5. Potential Cost Savings: While PRP does add to the overall cost of IVF, it may improve the chances of success, potentially reducing the need for multiple IVF cycles.
  6. Minimally Invasive: PRP injections are minimally invasive and typically involve minimal downtime for patients.

Is PRP Painful in IVF?

PRP injections are generally not considered painful, but the level of discomfort can vary from person to person. Patients often describe the sensation as similar to a mild pinprick or pressure at the injection site. The discomfort is typically brief and well-tolerated.

To minimize discomfort during PRP injections, healthcare providers may use topical anesthetics or numbing agents at the injection site. Additionally, the use of fine needles and the expertise of the healthcare professional can contribute to a more comfortable experience.

Conclusion

Platelet-rich plasma (PRP) is a versatile and promising therapeutic option in the field of fertility treatments. It offers hope to individuals facing various reproductive challenges, from low ovarian reserve to thin endometrial linings. When administered strategically, PRP can enhance the chances of successful IVF outcomes, improve sperm quality, and provide valuable solutions for infertility issues. Furthermore, PRP’s regenerative potential extends to other areas of medicine, making it an exciting field of ongoing research and innovation in the realm of reproductive health and beyond.

Testimonial

1000+ Happy Couples with real stories from IVF patients

My case was handed by Dr Mandavi Rai, she is very professional toward her work and All the staff members have been very helpful and friendly I believe it is one of the best gynecologist and ivf across Delhi NCR, if someone facing issue with infertility must visit indira ivf , sectors 18, Noida. Once again thank you so much Dr Mandavi rai and all the team members.

Surendra Pal

Hello everyone ,Iam very thankful to Indira IVF Noida center for their help.they helped me to achieve pregnancy after 10 years of long wait.it is the Best IVF center in noida.they have the best and supportive staff.most important is Dr Mandavi is very experienced and guides you well.she is the best doctor I will once again thanks the entire Indira IVF Noida team for their immense support 😘.

Ayush Gujjar

Thanks to Dr. Neha and Dr. Mandvi for this immense happiness which is possible just by their guidence and support, I have just started my journey. Special thanks to Ms.Ocean, she is very supportive and ready to answer all the doubts regarding any issue anytime. Thanks to all Indra IVF Noida team, all the members working there are very good and carries a smile on their faces which gives a positive vibes 🙏

neha chaudhary

Thank you Dr Madhavi Madam and all the staff at Noida center. They have provided all possible solutions to become parenthood's and our dreams journey have been started just. All the best and Good luck from our side to start your journey soon. You can get an good and wonderful experience and support from them. Most important is that couples need to prepare mentally and physical too for this wonderful feelings. Just need to extend your support on financial part who need it most.

mitul makwana

After struggling for last 5 years, We have wonderful experience with the doctor & whole staff of INDIRA IVF NOIDA CENTRE , Doctor Mandavi ma’am is very generous & simple . All the staff are very easy going & supportive. I would like to mention the name specially lovely Osheen ma’am, Shweta ma’am for guiding us in every situation. They are always available on phone call for any guidance & emergencies. They treat like family not like Clint. I would like to thanks Prabhat ji karan ji & all other staff too for their wonderful support . We wish them all the success & best wishes from bottom of our heart. Humble thanks! 🙏🙏🙏

PRIYA TIWARI

Thanks to Indira IVF and all the staff members of Noida centre..I have been trying for 4 years for pregnancy but there were no positive result..Then I heard about Indira IVF and the journey started and now my report is positive in first attempt..I am very greatfull to Dr Mandi Rai and her team...🤩🤩😊😊 Thanku so much to all of you♥️

jayant Kumar

I am very thankful to all indira ivf noida staff and Dr. Mandavi Rai. Noida centre is one of the best center of indira IVF. Doctor Mandavi Rai is so experienced doctor in her field. All the staff and doctor are very caring and helpful nature.They guide us every time when we need. I conceived my pregnancy in first attempt after 8 years of my marriage. Once again thanks to Dr. Mandavi Rai and her team. Best place for every infertile couple who want to be parents.

Radha thakuri

We had the best experience with Dr Mandavi Rai and her entire professional Team of Indira IVF Noida. Dr. Mandavi is very professional, caring, knowledgeable and helpful. They all made this journey easy for me. now I am 18 weeks pregnant and baby is on the way!! Thank You. Dr. Mandavi and Team for made our dream come true!!

Madhuri Mishra

We were trying for a long time for a baby but we failed everytime... When we came to Indira ivf centre , they helped us in every stage of our treatment and finally I got positive result ..... My whole journey during IVF dr. Mandavi mam guided us so well . Thank you so much for bringing happiness in our life..

Richa Sharma

Indira IVF Noida Sec 18: A team of very supportive staff and well experienced Dr. Mandavi Rai. After 7 years of marriage, we lost hope of having kids.Then we visited Indira IVF Sec 18 Noida and we got positive result under the expertise and professional team. Thanks to entire team and especially Dr. Mandavi Rai for make our dream comes true. If some1 have lost hope of having kids than must visit and consult Dr. Mandavi Rai and team. Thanks

Amit Sinha

Indira IVF Noida Sec 18: A team of very supportive staff and well experienced Dr. Mandavi Rai. After 7 years of marriage, we lost hope of having kids.Then we visited Indira IVF Sec 18 Noida and we got positive result under the expertise and professional team. Thanks to entire team and especially Dr. Mandavi Rai for make our dream comes true. If some1 have lost hope of having kids than must visit and consult Dr. Mandavi Rai and team. Thanks

Amit Sinha

I would like to thank Dr. Mandavi and the entire Noida team. I conceived in first attempt after 12years of marriage. The whole team is quite humble and helpful and the Dr. Mandavi is very approachable and kindly answers her patient’s questions and concerns. I am glad I chose Indira IVF Noida😊. I would highly recommend you to consult them if you are struggling with fertility issues. God Bless.

Ritu Singh

Fortunately we came to Indira Ivf and it is the best place to get it done. My husband and me have been married since last 8 years and got this biggest happy news just because of this centre. Dr Mandavi Rai is extremely efficient in her work and very polite , understanding and positive. Also the complete staff is very helping and supportive. They are there everytime you need them . They follow up with you on time nad take updates. I want to specifically thank Jr Doc, Monica, Osheen, Yamini for thier through out support . You guys rock 😃. Last but not he least a smiling face Prabhat bhaiya, you are a gem. Priya & Vaibhav Modi

Priya Gupta

We were trying for a long time for a baby but we failed everytime... When we came to Indira ivf centre , they helped us in every stage of our treatment and finally I got positive result ..... My whole journey during IVF dr. Mandavi mam guided us so well . Thank you so much for bringing happiness in our life..

Richa Sharma

This Center is a boon to many parents. They are supportive and Caring as well. Doctor and Staff Nurses give great advice and do the follow up on regular basis. Thanks to Noida 18 Indira IVF Team. Receptionist, Medical Store respresentative, Cashier and then the most valuable asset 3 angels 😇 of IVF. junior Doc, Staff Nurse Mam. Thanks Again 👍

Divakar nigam

After years trying to conceive, several losses, multiple failed from other fertility clinics with a frustrating diagnosis. I and my wife finally took descision to visit India and decided to choose Indira IVF fertility centre ( Noida , uttar Pradesh). When things aren't working right and you are struggling to get pregnant, this is the doctor you want on your side. Dr. Mandavi Rai is the perfect combination of knowledge and empathy. Each challenge she encounters, she attacks head on, and trust me, my case has a few of them! The phrase " Give up" is not in her vocabulary. She will find a solution. Dr Mandavi Rai's manner is wonderful. Now about staff .... Some of the best people you will ever know. They are all very knowledgeable in their field, treat you with kindness and respect, and makes themselves available for any questions and concerns, oftentimes going above beyond their job description to help you out.👍👍👍👍👍

Manjil Mandal

I had the best time with Dr Mandavi and her team from day one. She is so goood I can't explain in words. Before her I had consulted quite a few others doctors but I couldn't continue with any of them. Dr Mandavi is calm doctor who listens to concerns even if you ask a thousand times and never rushes into conclusions. She will take time to explain and then will help us make our decision. She has became nothing less than my family member and truly cherish my relationship with her. A big portion of her being the way she is goes to the wonderful team she has who are equally responsive, available at midnight, caring and super supportive. I am very thankful to Yamini ji, Monika ji and Prabhat ji and even Wasim ji who always gave a warm smile in my journey. I am very very thankful to everyone and spl Dr Mandavi for just being there for me then and even now and always going forward. Thanks a lot & God bless.

Urvashi Dube

A place where our dream of having a child actually turned to reality is Indira IVF Noida. We would like to thank Doctor Mandavi ma'am and her entire team for this beautiful experience. I conceived my pregnancy in first attempt after 7 years of my marriage. All credit goes to you Mandavi ma'am 🙏🏼❤️ Thank you for your kind and supportive nature throughout our journey. (Whoever is dreaming of becoming a parent, please do get your treatment done at this place.)

Saroj

I am very grateful to INDIRA IVF NOIDA Teem. They are the best IVF center in Noida. My wife conceived in first attempt. They have the best staff and best services. Dr. Mandavi Rai is the best doctor to consult.They have most affordable treatment plan. Than you soo much INDIRA IVF NOIDA.

Vedprakash Sharma

I am (Priyanka Rani) sharing my feedback here about Indira IVF Centre. There is no doubt about giving a 5-star rating because Dr. Madam and all the staff are very helpful. They guide us every time, when we needed them (some times on calls or what's up as well). I conceived my pregnancy on my first attempt after six years of marriage. Thanks a lot to Indira IVF (Dr. Mandavi Rai and her staff). It's just advice for Indira IVF call centre that it should be clear on the phone that all the IVF package details are given, and after using medicine, an approximate idea of the amount should be given because some times every person cannot cover medicine and injections after taking the IVF package. Because every person can not do the google for more details and can not contact to their relatives.

Piku Rani

I am so thankful to Dr mandavi rai is so experienced in her field. She is the best consultant in noida. My wife conceived after १५ years of our marriage. I recommend this indira ivf noida center to all the persons who want to become parents. The staff here is so cooperating and helpful they guide us properly in every time. I am thankful to all staffs here Dr monika, yamini, osheen, prabhat, waseem 😊😊. # best doctor.

Jagdish Chhimwal

I cannot express how grateful and satisfied I am with my experience at Indira IVF Noida, particularly with Dr. Mandavi Rai's expertise. From the very beginning, she demonstrated a caring and compassionate approach, answering all my questions and concerns with patience and empathy. The entire process was seamless, and I felt well-supported throughout my journey. Dr. Mandavi's knowledge and professionalism instilled confidence in me, and I was thrilled to achieve success in my first attempt at conception. The staff at Indira IVF Noida was also exceptional, providing a warm and welcoming environment that made a significant difference during this emotional and important time. The facilities were modern, clean, and well-maintained. I highly recommend Indira IVF Noida and Dr. Mandavi Rai to anyone seeking fertility treatments. My heartfelt thanks to the entire team for making my dream of becoming a parent a reality.

Abhi Gupta

I am delighted to share my heartfelt appreciation for the outstanding service provided by Indira IVF, Noida , Dr. Mandavi Rai and all the staff there. From the moment we entered the clinic, the warm and friendly atmosphere put us at ease. The professionalism and expertise displayed by the medical team were truly commendable. Their care and compassion throughout our fertility treatment journey were exemplary. Indira IVF's staff went above and beyond, creating an exceptional experience that we would highly recommend to others. Thank you Noida Team .😊

Sachin Tripathi

We were lost hope to have smile on our face s after diagonized with some critical issue, but Ms Dr. Mandvi Rai Mam and her team put a great effort to bring back smile. Thank you so much Indira IVF noida team. Noida team is very caring. I personally advise to people who are facing such issue please meet with doctors before time is up.

BRIJBHAN CHAUHAN

A very big Thanks to Indira IVF . The complete team of Indira IVF is very professional, transparent and responsive. Dr. Mandavi is so calm and her staff is superb.They all were very cooperative. They discussed the thing in detail and suggested all possible options. We were trying for pregnancy for 5 years . And then I got to know about Indira IVF treatment. Here we got success in the first attempt... I am so thankful for the entire team for their support and effort.

Neelam Pankaj

Its very good experience at Indra IVF . The success rate is quite high may be above 70%. Dr Mandvi Rai is very good , polite, easily approachable and sincere to her duty. In my opinion Indra IVF is the Best IVF center in Delhi NCR as well as in India. I wish for all Success to Indra IVF and to meet the expectations of the needy couple.

Raj Pratap Verma

Best IVF center in Noida. I conceived in 1st attempt after 11 years of my marriage. I want to thanks to Dr mandavi rai she is so experienced and expert in her field. Her entire is also so helpful. I also want to thanks to her entire team of indira ivf noida center junior doctor Monika, Yamini, Osheen, Neha, prabhat, Arjun, waseem. Thank you so much for giving us this happiness of parenthood in our live. I highly recommend this center.

Chanchala Chaudhary

I am very grateful to Dr Mandavi Rai for her guidance and support in achieving our pregnancy. it's the best IVF Cneter with est staff and support. All the patients who want to conceive should visit Noida center as they have the best staff and best doctor!!

Ram Vilash

Amazing experience with the staff and the doctor. Best class support and finally we are in the process of becoming parents. Staff will give personalised support and help throughout the process. Thanks Dr. Mandavi and her team for fulfilling our dream. Kudos and keep up the good work. Highly recommended !!

Sarvesh Pandey

Dr Mandvi and all her staff from admin, to medical, to reception to assistant everyone is very helpful. They listen to every single problem of yours carefully and will ensure all required support and help is given. We came here after a lot of disappointments. But they ensure the treatment and all alternatives are given in the starting only. Thank you again for the support and understanding

The Makeup Diaries!!

After struggling for last 5 years, We have wonderfulexperience with the doctor & whole staff of INDIRAIVF NOIDA CENTRE , Doctor Mandavi ma'am is verygenerous & simple . All the staff are very easy going& supportive. I would like to mention the namespecially lovely Osheen ma'am, Shweta ma'am forguiding us in every situation. They are alwaysavailable on phone call for any guidance &emergencies. They treat like family not like Clint. Iwould like to thanks Prabhat ji karan ji & all otherstaff too for their wonderful support . We wish themall the success & best wishes from bottom of ourheart. Humble thanks!

PRIYA TIWARI

Thank you Dr Madhavi Madam and all the staff at Noida center. They have provided all possible solutions to become parenthood's and our dreams journey have been started just. All the best and Good luck from our side to start your journey soon. You can get an good and wonderful experience and support from them. Most important is that couples need to prepare mentally and physical too for this wonderful feelings. Just need to extend your support on financial part who need it most.

Mitul Makwana

My case was handed by Dr Mandavi Rai, she is very professional toward her work and All the staff members have been very helpful and friendly I believe it is one of the best gynecologist and ivf across Delhi NCR, if someone facing issue with infertility must visit indira ivf , sectors 18, Noida. Once again thank you so much Dr Mandavi rai and all the team members.

Surendra Pal

best staff every one is helping and kind Dr Mandavi mam is so careful and helping and amezing visit for good care

Geetika Agarwal

We started visting Indira IVF after a refreaal from Mumbai Indira IVF; Dr.Mandavi and Team are good and have taken good care of the baby during pregnancy; they advised right hospital for delivery and supported us; Thanks to Shevali and Oshi alog with Dr.Mandavi

Parkash Gurazada
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